Software posted here is compiled for Windows x64 Edition. Please post more applications, they need not be free!
Anti-Virus
Avast!
NOD32
Symantec Antivirus
Audio/Video Editing/Production
Cakewalk Sonar x64
VirtualDub
Benchmarks
CineBench
FRAPS
Desktop Customisation
WindowBlinds
Disk mangement
FileDisk x64 (Unofficial)
WinImage
File Compression
7-Zip
Squeez
WinRAR (latest beta has x64 shell extensions)
Firewall
Tiny Firewall 64
Games
Far Cry x64 upgrade
Graphics
POV-Ray
Networking
PuTTy x64 (Unofficial)
System Utilties
Filemon x64
OpenGL Extensions Viewer
Prime95
Process Explorer
Regmon x64
StartupMonitor64
O&O Defrag (Beta!)
Tweaking Software
TweakUI64 (Unofficial)
Web Software:
Mozilla Firefox (Unofficial x64 build)
Sun Java x64