Just had a friend install this on a machine she originally has MSE on, as well as the free Malware-Bytes application just to hunt down some bit of malware that's been plaguing her system. They never found anything, and we're both too busy to meet up and get it fixed.
BitDefender came up with 52 threats... I really hope this fixes her system, and will be dropping what I've been using when I get home for this on my desktop.
It surprises me that Malwarebytes would miss such an infected machine
My guess is that the malware was rendering MB inactive, I've seen viruses cause machines to refuse to install / update MB many times