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Scientists design a potential drug compound that attacks Parkinson's disease on 2 fronts

JUPITER, FL-- Scientists from the Florida campus of The Scripps Research Institute (TSRI) have found a compound that could counter Parkinson's disease in two ways at once.

 

In a new study published recently online ahead of print by the journal ACS Chemical Biology, the scientists describe a "dual inhibitor"- two compounds in a single molecule-- that attacks a pair of proteins closely associated with development of Parkinson's disease.

 

"In general, these two enzymes amplify the effect of each other," said team leader Phil LoGrasso, a TSRI professor who has been a pioneer in the development of JNK inhibitors for the treatment of neurodegenerative diseases. "What we were looking for is a high-affinity, high-selectivity treatment that is additive or synergistic in its effect

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I don't know if I missed it or not, but is this drug a preventative vaccine, cure, or simply something to alleviate symptoms? In any case, it's an amazing breakthrough. Hopefully it leads to more in the future.

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