The Registry is a heart and soul of any Windows system. It contains information that controls how your Windows appears and how it behaves. Most applications today use registry to store configuration and other important data. When you install an application, a new registry entries will be created. This entries will automatically be deleted when you uninstall the application. Unfortunately, it is not always work that way. Sometimes, you will find that some applications fail to remove their own registry entries. This entry will become obsolete.
After a long period, after installing and uninstalling a lot number of applications, your Windows registry will contain a large number of obsolete entries. This will significantly increase the registry size and thus will slowdown your computer, because Windows will need more time to load, search, and read data from registry. To keep your computer in top performance, it is recommended to periodically clean your Windows registry.
License: Free for non commercial use
Download: TweakNow RegCleaner
Screenshot: TweakNow RegCleaner 1.2.6
News source: TweakNow RegCleaner
After a long period, after installing and uninstalling a lot number of applications, your Windows registry will contain a large number of obsolete entries. This will significantly increase the registry size and thus will slowdown your computer, because Windows will need more time to load, search, and read data from registry. To keep your computer in top performance, it is recommended to periodically clean your Windows registry.
License: Free for non commercial use
Why using TweakNow RegCleaner?
Fast: using a high performance engine, TweakNow RegCleaner quickly scan your registry to find obsolete entries.
Accurate: using complex algorithm TweakNow RegCleaner accurately identify obsolete entries.
Secure: TweakNow RegCleaner automatically create backup file before deleting obsolete entries from your registry.
Flexible License: TweakNow RegCleaner available in two licenses, commercial and non commercial (free).
Just try it ! You find the TweakNow RegCleaner is the fastest and the most reliable registry cleaner program available today.

http://www.neowin.net/forum/index.php?showtopic=145587
so sad to see this
Anyway, has anybody tried this? It would be a great app if it was reliable.
not sure about using this under xp or 2k
Simple rule: When it comes to Windows maintenance, nothing is simple.
Except a full windows clean reinstallation!
Commenting has either been disabled on this article or you are not logged in. Click here to login or register, its free!
Note: Anonymous commenting is disabled in order to keep the quality of responses to a high standard.