Jump to content



Photo

Single antibody found to both prevent and cure flu

cailfornia scripps research institute influenza a viruses

  • Please log in to reply
5 replies to this topic

#1 Hum

Hum

    totally wAcKed

  • 62,140 posts
  • Joined: 05-October 03
  • Location: Odder Space
  • OS: Windows XP, 7

Posted 17 September 2012 - 15:26

A single antibody has been found to prevent the influenza virus from taking hold of host cells, as well as cure animals that are already infected, UT San Diego reported.

Researchers from the Scripps Research Institute in La Jolla, Calif., examined thousands of proteins in order to identify the antibody. After analyzing the influenza virus in its 3-D crystalline form, the scientists discovered the antibody attacks a structure of the virus that is used to take hold of healthy cells.

Study author Ian Wilson, a professor of structural biology at Scripps, said this discovery of focused binding has “never been seen before.”

“It gives us some good idea about designs for vaccines and therapies,” Wilson said.

The study involved collecting bone marrow from patients exposed to different strains of the influenza virus. According to UT San Diego, bone marrow essentially acts as a storage facility for all the antibodies a person’s body has ever produced, so the study’s researchers knew the antibody they were looking for would be there.

Next, the researchers created a catalogue of billions of flu antibodies, allowing them to pinpoint Co5 – an antibody able to bind to influenza A viruses. Added to petri dishes of healthy cells and influenza A, Co5 stopped the cells from getting infected. Mice studies echoed the same results, with Co5 preventing influenza in mice. Also, when mice were given Co5 after having contracted the flu, all were cured.

"Clearly, the holy grail is a universal flu vaccine, and this is another important step toward that,” Wilson said.

source


#2 -Razorfold

-Razorfold

    Neowinian Senior

  • 9,656 posts
  • Joined: 16-March 06
  • OS: Windows 8
  • Phone: Nokia Lumia 900

Posted 17 September 2012 - 15:28

"Clearly, the holy grail is a universal flu vaccine, and this is another important step toward that,” Wilson said.


And then 10 years from now...a super resistant strain of the virus is detected. MANKIND HAS 1 YEAR TO LIVE.

#3 +Xinok

Xinok

    Resident Reresident

  • 3,491 posts
  • Joined: 28-May 04
  • Location: Shikaka
  • OS: Windows 7 x64
  • Phone: Galaxy S3 (Wicked)

Posted 17 September 2012 - 20:02

And then 10 years from now...a super resistant strain of the virus is detected. MANKIND HAS 1 YEAR TO LIVE.

I thought the same thing. The flu sucks, but a drug-resistant flu is even worse. Of course, I'd love to see them produce a drug that doctors could prescribe to patients with a high risk for complications.

#4 Max Norris

Max Norris

    Neowinian Senior

  • 4,262 posts
  • Joined: 20-February 11
  • OS: Windows, BSD Unix, Occasionally OSX or Linux
  • Phone: HTC One (Home) Lumia 1020 (Work)

Posted 17 September 2012 - 20:06

And then 10 years from now...a super resistant strain of the virus is detected. MANKIND HAS 1 YEAR TO LIVE.

Captain Trips?

#5 kafeleip

kafeleip

    Resident One Post Wonder

  • 1 posts
  • Joined: 14-November 12

Posted 14 November 2012 - 16:00

A single antibody has been found to prevent the influenza virus from taking hold of host cells, as well as cure animals that are already infected, UT San Diego reported.

Researchers from the Scripps Research Institute in La Jolla, Calif., examined thousands of proteins in order to identify the antibody. After analyzing the influenza virus in its 3-D crystalline form, the scientists discovered the antibody attacks a structure of the virus that is used to take hold of healthy cells.

Study author Ian Wilson, a professor of structural biology at Scripps, said this discovery of focused binding has “never been seen before.”

“It gives us some good idea about designs for vaccines and therapies,” Wilson said.

The study involved collecting bone marrow from patients exposed to different strains of the influenza virus. According to UT San Diego, bone marrow essentially acts as a storage facility for all the antibodies a person’s body has ever produced, so the study’s researchers knew the antibody they were looking for would be there.

Next, the researchers created a catalogue of billions of flu antibodies, allowing them to pinpoint Co5 – an antibody able to bind to influenza A viruses. Added to petri dishes of healthy cells and influenza A, Co5 stopped the cells from getting infected. Mice studies echoed the same results, with Co5 preventing influenza in mice. Also, when mice were given Co5 after having contracted the flu, all were cured.

"Clearly, the holy grail is a universal flu vaccine, and this is another important step toward that,” Wilson said.

source


an interesting news. so it's co5... what progress so far in the science of flu have been made so far based on this report? i'm sure everybody would interested to know.

#6 Growled

Growled

    Neowinian Senior

  • 41,508 posts
  • Joined: 17-December 08
  • Location: USA

Posted 15 November 2012 - 01:33

And then 10 years from now...a super resistant strain of the virus is detected. MANKIND HAS 1 YEAR TO LIVE.


Of course. Mother Nature is always two steps ahead of us.