I do not use the AdGuard extension. I have uninstalled both the uBlock and Stylus extensions, as well as the Tampermonkey extension, since I began using AdGuard for Windows 7 months ago.
It does not use any extension APIs, it modifies traffic system wide using a local proxy. AdGuard performs all the functions of uBlock, as well as additional features such as HTTPS filtering, cosmetic (user scripts and user styles), as well as DNS. It works with any browser and application. I don't understand why you consider the desktop program to be useless...