Tom Posted December 20, 2011 Share Posted December 20, 2011 http://www.cbc.ca/news/canada/story/2011/12/20/hiv-vaccine-western.html A vaccine that may prevent HIV has been given the green light by the U.S. Food and Drug Administration to begin clinical trials in humans, according to Canadian researchers. The announcement was made on the campus of the University of Western Ontario in London, Ont. "We have gone through so many different challenges to come to this point," said Dr. Chil-Yong Kang, a researcher and professor at Western's Schulich School of Medicine and Dentistry. "This is the first time that I feel very happy and comfortable to initiate this human clinical trial." Scientists at the University of Western Ontario, financially backed by the pharmaceutical venture company Sumagen, developed the vaccine, which is based on a genetically modified killed whole virus. The vaccine stimulated a strong immune response in early testing and appears to have no adverse effects, according to the researchers. Awesome. (Y) Link to comment Share on other sites More sharing options...
shockz Posted December 20, 2011 Share Posted December 20, 2011 Wonder how they'll test to see if it works... /s Link to comment Share on other sites More sharing options...
nominak Posted December 20, 2011 Share Posted December 20, 2011 This is amazing. I'm surprised the FDA actually approved this. Link to comment Share on other sites More sharing options...
theclueless Posted December 20, 2011 Share Posted December 20, 2011 maybe post-exposure vaccination? Link to comment Share on other sites More sharing options...
User6060 Posted December 20, 2011 Share Posted December 20, 2011 Canada FTW :D I know plenty of Western students and their health and med programs are pretty sweet Link to comment Share on other sites More sharing options...
shakey Posted December 20, 2011 Share Posted December 20, 2011 Wonder how they'll test to see if it works... /s *shot given* Ok, and now we are going to put in some HIV.... a month passes Ok... that didn't work sir. You now have full blown HIV... Link to comment Share on other sites More sharing options...
Glassed Silver Posted December 20, 2011 Share Posted December 20, 2011 *shot given* Ok, and now we are going to put in some HIV.... a month passes Ok... that didn't work sir. You now have full blown HIV... :p Guess the first testers that would be running for this are people who like sex without condoms with strangers (does exist after all). If their infection rate is zero I guess a second test with actually injecting the HI virus would be made. Good news, indeed. Possibly cure for cancer AND vaccine against AIDS in one year, awesome! (Y) Boy is 2011 "up and down"y... Glassed Silver:mac Link to comment Share on other sites More sharing options...
shakey Posted December 20, 2011 Share Posted December 20, 2011 :p Guess the first testers that would be running for this are people who like sex without condoms with strangers (does exist after all). If their infection rate is zero I guess a second test with actually injecting the HI virus would be made. Good news, indeed. Possibly cure for cancer AND vaccine against AIDS in one year, awesome! (Y) Boy is 2011 "up and down"y... Glassed Silver:mac Yeah, great year for science, **** for everything else lol. If there was 1 test that I'm sure is worse than the guy who test the razors that won't cut you, it is this one. Glassed Silver 1 Share Link to comment Share on other sites More sharing options...
DocM Posted December 20, 2011 Share Posted December 20, 2011 Wonder how they'll test to see if it works... /s Volunteers, not infrequently priests & nuns. It's beendone with previous vaccine trials, including HIV. Link to comment Share on other sites More sharing options...
Dot Matrix Posted December 20, 2011 Share Posted December 20, 2011 Why do I get the feeling, that it'll be kept around in a lab somewhere like smallpox? Link to comment Share on other sites More sharing options...
DocM Posted December 20, 2011 Share Posted December 20, 2011 Why do I get the feeling, that it'll be kept around in a lab somewhere like smallpox? Smallpox is kept in Level 4 labs in the US and Russia for research in case it's not really gone but hiding and a stealt strain emerges again. Link to comment Share on other sites More sharing options...
shakey Posted December 20, 2011 Share Posted December 20, 2011 What was that show that said something like, " Ya, when I became president, I gave all the richest and most powerful people aids. In 2 months we had a cure!" I think it was chappell show.. Link to comment Share on other sites More sharing options...
FMH Posted December 20, 2011 Share Posted December 20, 2011 That's big! Link to comment Share on other sites More sharing options...
M_Lyons10 Posted December 20, 2011 Share Posted December 20, 2011 This would be really awesome if it works. It's really about time something was done about this disease. Link to comment Share on other sites More sharing options...
Dot Matrix Posted December 20, 2011 Share Posted December 20, 2011 This would be really awesome if it works. It's really about time something was done about this disease. We've been working up to it for a whilwe now. Even without a cure, HIV+ patients can still lead normal lives, and live longer than HIV+ patients 20 years ago. Link to comment Share on other sites More sharing options...
M_Lyons10 Posted December 20, 2011 Share Posted December 20, 2011 We've been working up to it for a whilwe now. Even without a cure, HIV+ patients can still lead normal lives, and live longer than HIV+ patients 20 years ago. Well yeah, but I meant a cure. Not just prolonging their lives (And their potential to infect others)... Link to comment Share on other sites More sharing options...
Skwerl Posted December 20, 2011 Share Posted December 20, 2011 Yeah, great year for science, **** for everything else lol. If there was 1 test that I'm sure is worse than the guy who test the razors that won't cut you, it is this one. I?m currently a volunteer in an HIV vaccine trial, and you really are not put into danger of contracting the virus from the vaccine itself. Recombinant DNA is used in these studies. Enzymes are used to attach proteins that resemble parts of HIV (synthesized with PCRS) to a disabled adenovirus. That dummy virus then *looks* like HIV, even though it can?t do anything but get attacked by your immune system when it launches its response. The vaccine, in this manner, is really quite safe. Oddly enough, in the study prior to the one I am in, men who already had antibodies for the adenovirus type 5 used for the rDNA dummy, had a statistically significant greater chance of contracting HIV. They did not get HIV from the vaccine, but it did appear to make them more susecptible to infection. Those are the surprises these trials can sometimes expose. Glassed Silver 1 Share Link to comment Share on other sites More sharing options...
shakey Posted December 20, 2011 Share Posted December 20, 2011 I?m currently a volunteer in an HIV vaccine trial, and you really are not put into danger of contracting the virus from the vaccine itself. Recombinant DNA is used in these studies. Enzymes are used to attach proteins that resemble parts of HIV (synthesized with PCRS) to a disabled adenovirus. That dummy virus then *looks* like HIV, even though it can?t do anything but get attacked by your immune system when it launches its response. The vaccine, in this manner, is really quite safe. Oddly enough, in the study prior to the one I am in, men who already had antibodies for the adenovirus type 5 used for the rDNA dummy, had a statistically significant greater chance of contracting HIV. They did not get HIV from the vaccine, but it did appear to make them more susecptible to infection. Those are the surprises these trials can sometimes expose. Thanks. Good information, and good luck as well. Link to comment Share on other sites More sharing options...
Dot Matrix Posted December 20, 2011 Share Posted December 20, 2011 I?m currently a volunteer in an HIV vaccine trial, and you really are not put into danger of contracting the virus from the vaccine itself. Recombinant DNA is used in these studies. Enzymes are used to attach proteins that resemble parts of HIV (synthesized with PCRS) to a disabled adenovirus. That dummy virus then *looks* like HIV, even though it can?t do anything but get attacked by your immune system when it launches its response. The vaccine, in this manner, is really quite safe. Oddly enough, in the study prior to the one I am in, men who already had antibodies for the adenovirus type 5 used for the rDNA dummy, had a statistically significant greater chance of contracting HIV. They did not get HIV from the vaccine, but it did appear to make them more susecptible to infection. Those are the surprises these trials can sometimes expose. Damn. Best of luck to you. Link to comment Share on other sites More sharing options...
Charisma Veteran Posted December 20, 2011 Veteran Share Posted December 20, 2011 This is amazing. I'm surprised the FDA actually approved this. Really? They approve a lot of things, some of which are pretty sketchy and untested... Glassed Silver 1 Share Link to comment Share on other sites More sharing options...
ArialBlue Posted December 20, 2011 Share Posted December 20, 2011 Those take retrovirals die from the retroviral effects and not HIV itself? Link to comment Share on other sites More sharing options...
tiagosilva29 Posted December 20, 2011 Share Posted December 20, 2011 I don't trust the FDA. sweetpoison07 1 Share Link to comment Share on other sites More sharing options...
Ravensky Posted December 20, 2011 Share Posted December 20, 2011 I am guessing testing on voluntary terminal patients. Link to comment Share on other sites More sharing options...
ArialBlue Posted December 20, 2011 Share Posted December 20, 2011 I am guessing testing on voluntary terminal patients. Death Row inmates would have been a better choice. Link to comment Share on other sites More sharing options...
Glassed Silver Posted December 20, 2011 Share Posted December 20, 2011 Really? They approve a lot of things, some of which are pretty sketchy and untested... If you're looking for agencies that hold back on approving new stuff, look no further than the EU or more specifically Germany. Not saying this with a negative tone, by the way... :) Doesn't mean we don't get sh**, too, but yeah... Glassed Silver:mac Link to comment Share on other sites More sharing options...
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